Confidence Intervals for Seroprevalence
نویسندگان
چکیده
This paper concerns the construction of confidence intervals in standard seroprevalence surveys. In particular, we discuss methods for constructing proportion individuals a population infected with disease using sample antibody test results and measurements test’s false positive negative rates. We begin by documenting erratic behavior coverage probabilities Wald percentile bootstrap when applied to this problem. then consider two alternative sets constructed inversion. The first set are approximate, either asymptotic or approximation finite-sample distribution chosen statistic. several choices statistic, including maximum likelihood estimators generalized ratio statistics. show simulation that, at empirically relevant parameter values sizes, these close their nominal level approximately equi-tailed. second shown contain true value probability least equal level, but can be conservative finite samples.
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ژورنال
عنوان ژورنال: Statistical Science
سال: 2022
ISSN: ['2168-8745', '0883-4237']
DOI: https://doi.org/10.1214/21-sts844